The 2021 Northern Iowa Panthers football team represented the University of Northern Iowa in the 2021 NCAA Division I FCS football season.

The Panthers competed as members of the Missouri Valley Football Conference and were led by 21st-year head coach Mark Farley.

They played their home games at UNI-Dome in Cedar Falls, Iowa.

[1][2] at Jack Trice Stadium • Ames, IA at Fargodome, Fargo, ND at Plaster Stadium • Springfield, MO

This college football 2020s season article is a stub.