The 2021 Stony Brook Seawolves baseball team represented Stony Brook University during the 2021 NCAA Division I baseball season.

The Seawolves played their home games at Joe Nathan Field as a member of the America East Conference.

The 2020 Stony Brook Seawolves baseball team notched a 6–9 (0–0) regular-season record.

The season prematurely ended on March 12, 2020, due to concerns over the COVID-19 pandemic.

*Denotes non–conference game • Schedule source • Rankings based on the teams' current ranking in the D1Baseball poll