The 2022–23 AS Trenčín season was the club's 23rd season in the Slovak Super Liga and 12th consecutive.

AS Trenčín participated in the Fortuna Liga and Slovak Cup.

As of 14 January 2023[2] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss [5] Source: Competitions