[1][2][3] In their first match of the UEFA Women's Champions League group stage, Barcelona surpassed their previous goal-scoring record of six goals in one game in the competition after winning 9–0 against Benfica.

On 3 June, Barcelona won the UEFA Women's Champions League for the second time in the team's history, mounting a comeback to win 3–2 against VfL Wolfsburg in the final.

[22] On 5 July, Barcelona announced that captain Alexia Putellas had suffered an anterior cruciate ligament injury in her left knee while training with the Spanish national team in England at the Euro 2022 tournament.

[26][27][28] On 22 July, Barcelona's Nigerian striker Asisat Oshoala won the African Women's Footballer of the Year award for a record 5th time.

[40] On 23 August, Barcelona retained the Joan Gamper Trophy after beating Montpellier 6–0 at Estadi Johan Cruyff; midfielder Patri Guijarro was named MVP of the match.

[48] On 30 August, Barcelona announced that they reached an agreement with the packaging company GLS Group, which became the official logistic partner of the squad and will remain a global sponsor of the club for the next three seasons, until 30 June 2025.

[53] On 17 September, Barcelona started off the new season with a 2–0 win against Granadilla Tenerife, with goals from Caroline Graham Hansen and the new signing Geyse Ferreira.

[62] On 15 October, following the international break, Barcelona continued their dominance, taking their fourth straight win in the league by beating Athletic Club 0–3 with goals from Clàudia Pina, Geyse Ferreira and Mariona Caldentey.

The core strategies for this alliance involve promoting healthy and active lifestyles, fostering new talents, and a clear investment in women's empowerment.

[73][74] On 21 October, captain Alexia Putellas won the Golden Player Woman award presented by the Italian sport magazine Tuttosport.

[80][81][82] On 27 October, Barcelona won their second consecutive group stage match of the season against Rosengård and claimed their seventh win in a row in all competitions with a 1–4 result.

[89][90][91] By the end of the month, the team's continued success without their injured players, especially Putellas, was praised, as was the incorporation of summer signings, particularly Bronze, Walsh and Geyse.

Clàudia Pina scored twice, with Asisat Oshoala, Fridolina Rolfö, Mapi León, Salma Paralluelo, Ana-Maria Crnogorčević and Geyse Ferreira each contributing to the victory.

Alexia Putellas was crowned as the Best Women's Catalan Player of the Year for a record fourth time; she received 51.2% of the jury votes and beat her teammate Aitana Bonmatí (46.3%) to the prize.

[112][113][114][115] Barcelona also set the record for the highest ever attendance for a Women's Champions League group stage game, and the fourth-highest of all Women's Champions League matches (the top two were also set at Camp Nou), with a record crowd of 46,967 spectators, even as the south stand was closed for renovation and a 2022 FIFA World Cup match was being played at the same time.

[123][124][125] On 10 December, Barcelona bounced back from the setback with a 4–0 win against Alhama, with Clàudia Pina, Salma Paralluelo, Bruna Vilamala and Asisat Oshoala getting on the scoresheet.

[130] Barcelona goalkeeper Sandra Paños saved two penalty kicks during the match, both near the close of the game and each by correctly diving in a different direction.

[137][138] Having already made it out of the Champions League group stage, Barcelona faced Rosengård, who were already eliminated, at home at the Camp Nou on 21 December, for their last match of the year.

Barcelona won 9–0 away, with Bruna Vilamala scoring the first hat-trick of the season, Aitana Bonmatí and Salma Paralluelo each netting two goals, and Geyse Ferreira and Mariona Caldentey also adding to the tally.

[159] Barcelona started their Supercopa defense against Real Madrid on 19 January 2023, in the second Women's Clásico of the season, which they won 3–1 after extra-time, advancing to the final thanks to goals from Clàudia Pina, Mariona Caldentey and Salma Paralluelo.

[163][164][165][166] During the winners' ceremony after the match, spectators noted that both teams were made to collect their medals from tables on the pitch; nobody from the RFEF presented Barcelona with their champions' cup; and it took some time before an official gave Aitana her MVP trophy.

[189] On 31 January, at the end of the winter transfer window, Barcelona signed Italian midfielder Giulia Dragoni, to join the B side.

[194][195][196][197] The draw for the Champions League knockout stages was held on 10 February at UEFA headquarters in Nyon, with the full bracket to the final announced.

[200][201] The FIFA FIFPRO Women's World Squad was announced on 13 February, with eight Barcelona players making the 23-player list: Sandra Paños was one of three goalkeepers; Lucy Bronze, Mapi León and Irene Paredes were among the seven defenders; and Aitana Bonmatí, Caroline Graham Hansen, Alexia Putellas, and Keira Walsh made up over half of the midfield.

Though the last avenue of sporting appeal, Barcelona would still be able to challenge the decision in a legal court, which Catalan state broadcaster CCMA suggested they may choose to do for precedent.

[232] On 21 March, Barcelona took a narrow 1–0 away victory against Roma in the first leg of their Champions League quarter-finals tie with a goal from Salma Paralluelo, in front of a record Italian women's club football attendance of 39,454 spectators at the Stadio Olimpico.

[254] Five days later, the return leg of the semi-final took place on 27 April at Camp Nou in front of a crowd of 72,262 spectators, the third-largest in the competition's history.

[260] The first team's league title was their fourth consecutive, and a record eighth victory; to achieve it, they beat Sporting de Huelva 3–0 in front of 5,289 supporters at Estadi Johan Cruyff.

[267] The team began May continuing their winning streak, beating Real Sociedad 5–2 away for their 27th consecutive victory in the 2022–23 league season, 62nd in total.

Barcelona started their Supercopa defense against Real Madrid on 19 January 2023, in the second Women's Clásico of the season, where they won 3–1 after extra-time and advanced to the final.