The 2022 ABA League Second Division Playoffs is the basketball play-off tournament that decides the winner of the 2021–22 ABA League Second Division season.

The winner of the play-offs qualifies for the 2022–23 ABA League First Division.

Source[1] In April 2021, it was announced that the Playoffs will be played in Skopje, North Macedonia.

[2] Knock-out elimination phases were played under single-game format.

Quarterfinals were played on 13 April 2022.