[1] The winners of the FAI Cup earns automatic qualification for the 2023–24 UEFA Europa Conference League.
The FAI Cup is a knockout competition with 38 teams taking part.
The round included three teams from the seventh tier, the lowest-ranked teams remaining in the competition: Pike Rovers, Salthill Devon and Villa FC.
Con Murphy hosted proceedings with former FAI Cup winners Alan Keane and Declan 'Fabio' O'Brien making the draw.
The draw for the quarter final took place on 30 August 2022 and all ties were played the week ending Sunday 18 September 2022.