FC Tobol were the defending champions after winning their second title the previous season.
On 11 March, Shakhter Karagandy were awarded a 3-0 technical victory over Astana after Astana fielded seven foreign players on the pitch at the same time during their match on 5 March 2022.
They were replaced by Aksu and Maktaaral from the Kazakhstan First League (both promoted to the top division for the first time in their history).
Note: Flags indicate national team as has been defined under FIFA eligibility rules.
Aleksandr Mokin & Timur Akmurzin both played in Tobol's 4-0 victory over Ordabasy on 27 August 2022 [49][50][51]