[1][2] The Sooners lost thirteen players via transfer portal for the 2022 season.

[24] 2022 Preseason All-Big 12 teams Source:[26] Oklahoma and the Big 12 announced the 2022 football schedule on December 1, 2021.

The Sooners will host 2 non-conference games against UTEP and Kent State and will travel to Nebraska.

[29] Quarterback Running back Wide receiver Tight end Long snapper Offensive line Defensive line Linebacker Defensive back Placekicker Punter

True Freshman at Gaylord Family Oklahoma Memorial Stadium • Norman, OK at Gaylord Family Oklahoma Memorial Stadium • Norman, OK at Memorial Stadium • Lincoln, NE at Gaylord Family Oklahoma Memorial Stadium • Norman, OK at Amon G. Carter Stadium • Fort Worth, TX at Cotton Bowl • Dallas, TX at Gaylord Family Oklahoma Memorial Stadium • Norman, OK at Jack Trice Stadium• Ames, IA at Gaylord Family Oklahoma Memorial Stadium • Norman, OK at Milan Puskar Stadium • Morgantown, WV at Gaylord Family Oklahoma Memorial Stadium • Norman, OK at Jones AT&T Stadium • Lubbock, TX at Camping World Stadium • Orlando, FL Key: POS: Position, SOLO: Solo Tackles, AST: Assisted Tackles, TOT: Total Tackles, TFL: Tackles-for-loss, SACK: Quarterback Sacks, INT: Interceptions, BU: Passes Broken Up, PD: Passes Defended, QBH: Quarterback Hits, FR: Fumbles Recovered, FF: Forced Fumbles, BLK: Kicks or Punts Blocked, SAF: Safeties, TD : Touchdown Oklahoma vs Non-Conference Opponents Oklahoma vs Big 12 Opponents Oklahoma vs All Opponents The NFL draft was held at Arrowhead Stadium in Kansas City, MO on April 27–29, 2023.