The club moved to MLS Next Pro for the season after previously playing in USL League One.
During the regular season, Toronto FC II won the Northeast Division and finished second in the Eastern Conference.
Roster slots 1 through 24 are reserved for players on professional contracts.
The remaining 11 slots are for amateur MLS Academy players (who are unpaid, must be under the age of 21, be part of the team's academy, and have never signed a professional contract or played in the NCAA).
Updated to match played September 24, 2022Source: Stats Crew