The 2023 Omloop Het Nieuwsblad was a road cycling one-day race that took place on 25 February 2023 in Belgium, starting in Gent and finishing in Ninove.

The race was won by Belgian rider Lotte Kopecky of SD Worx in a solo finish, beating the peloton by 11 seconds.

[2] Running for the first time as a UCI Women's World Tour event, the course was lengthened to 132.3 kilometres (82.2 mi).

[2] Dutch rider Lorena Wiebes of SD Worx won the bunch sprint for second place.

[2] Amanda Spratt of Trek–Segafredo retained the leaders jersey of the UCI Women's World Tour.