The 2024–25 High Point Panthers women's basketball team represents High Point University during the 2024–25 NCAA Division I women's basketball season.

The Panthers, led by sixth-year head coach Chelsea Banbury, play their home games at the Qubein Center in High Point, North Carolina as members of the Big South Conference.

The Panthers finished the 2023–24 season 20–12, 14–2 in Big South play, to finish as Big South regular season champions.

[1] They would defeat UNC Asheville,[2] before being upset by #5 seed and eventual tournament champions Presbyterian in the semifinals of the Big South tournament.

[3] They received an automatic bid to the WBIT,[4] where they would be defeated by Virginia in the first round.