The 2025 Cleveland Open was a professional tennis tournament played on indoor hardcourts.

It was the seventh edition of the tournament which was part of the 2025 ATP Challenger Tour.

It took place in Cleveland, Ohio, United States between January 27 and February 2, 2025.

[1][2] The following players received wildcards into the singles main draw: The following player received entry into the singles main draw using a protected ranking: The following players received entry from the qualifying draw: