3-Quinuclidinone is a bicyclic organic compounds with chemical formula HC(C2H4)2(C(O)CH2)N. Its basicity is indicated by the pKa of the conjugate acid, which is 7.2.

In contrast quinuclidine is about 100x more basic.

[2] Its hydrochloride salt can be synthesized by a Dieckman condensation:[3] It is a precursor to quinuclidine.

Organic reduction of 3-quinuclidone gives the compound quinuclidine, structurally related to DABCO, which has one additional bridgehead nitrogen atom.