It provided airlift support and conducted airborne drops and glider operations for Allied troops in Burma, central China, and French Indochina in the last year of World War II.

On 1 October 2005, the squadron was again activated as part of an overall expansion of the Air Force Special Operations Command.

It provided airlift support and flew aerial resupply missions in support of various commando units, such as Merrill's Marauders and the Chindits and conducted airborne drops and glider operations for Allied troops in Burma, central China, and French Indochina in the last year of World War II.

The squadron initially operated Curtiss C-46 Commandos, but also Douglas C-47 Skytrains, and Helio U-10 Courier, and North American T-28 Trojans until moving to England Air Force Base, Louisiana in 1966.

The squadron frequently deployed crews and airplanes to Southeast Asia for civic action and counterinsurgency missions.