3 lbs (pronounced "three pounds") is an American medical drama television series created by Peter Ocko, that aired on CBS from November 14, 2006, to November 7, 2008, replacing the cancelled series Smith.

[1][2] The title refers to the fact that the average human brain weighs approximately three pounds.

The show follows the medical careers of prominent brain surgeon Doctor Douglas Hanson (played by Stanley Tucci) and his protégé, Jonathan Seger.

The original pilot was filmed with Dylan McDermott as Dr. Doug Hanson and Reiko Aylesworth as Dr. Adrienne Holland.

The series then filmed in New York City, at the request of Tucci, who did not want to be away from home during production.