A previous unit with the same designation was organized in 1989, headquartered at Sycamore and then Machesney Park as part of the 404th Chemical Brigade before its 1997 inactivation.

A unit with the same designation was headquartered at Sycamore as part of the 404th Chemical Brigade, organized on 1 July 1989 and activated in September of that year.

[2] It was relocated to Machesney Park on 1 October 1995; the Sycamore armory was taken over by the newly activated Battery C, 2nd Battalion, 122nd Field Artillery.

Eight of its personnel received Bronze Stars for actions during the deployment before it returned to the United States in September 2009.

[13] With about 120 personnel, the 444th Chemical Company was mobilized for a deployment to Kuwait in February 2012, providing security at Camp Virginia[14] before returning to the United States in December.