[6][7] Its energetic effects can be very strong at high doses, increasing normal heart rate considerably.

[4] These mechanisms might help explain anecdotal reports of antidepressant and anxiolytic effects from modest doses of this compound.

However, subsequent research contradicted the preceding findings and found that 5-MeO-MiPT did not significantly bind to or inhibit the human monoamine transporters.

[2] Based on Shulgin's personal experience,[12] dosage for an adult male of approximately 6' and 200lbs: DOSAGE: 4 - 6 mg, orally; 12 - 20 mg, smoked DURATION : 4 - 6 hrs Exposing compounds to the reagents gives a colour change which is indicative of the compound under test.

[13] Scheduled in government decree on psychoactive substances banned from the consumer market.

[18][19][20] As of September 2024, it is in phase 1 clinical trials in healthy individuals in the United States and the European Union.

[18][19][20] The drug was selected for development via artificial intelligence (AI)-assisted processing of 70,000 online trip reports that aimed to identify a psychedelic with unique subjective effects deemed promising for pharmaceutical development.