The regiment was attached to 21st Brigade, Army of the Ohio, January 1862.
21st Brigade, 6th Division, II Corps, Army of the Ohio, to November 1862.
2nd Brigade, 1st Division, Left Wing, XIV Corps, Army of the Cumberland, to January 1863.
2nd Brigade, 1st Division, XXI Corps, Army of the Cumberland, to October 1863.
2nd Brigade, 2nd Division, IV Corps, Army of the Cumberland, to June 1865.
The 57th Indiana Infantry mustered out of service at San Antonio, Texas on December 14, 1865.
Buell's Campaign in northern Alabama and middle Tennessee, along Memphis & Charleston Railroad June to August.
March to Louisville, Kentucky, in pursuit of Bragg August 21-September 26.
Passage of the Cumberland Mountains and Tennessee River and Chickamauga Campaign August 17-September 22.
Occupation of Chattanooga, September 9, and garrison duty there during Chickamauga Campaign.
Operations on line of Pumpkin Vine Creek and battles about Dallas, New Hope Church, and Allatoona Hills May 25-June 5.
Ruff's Station, Smyrna Camp Ground, July 4.
Ordered to New Orleans, Louisiana, June 16; then to Texas July.
Duty at Green Lake and San Antonio until December.