The 65th Regiment Indiana Infantry, was organized in Princeton and recruited throughout the southern Indiana counties to fight in the American Civil War.

Original recruitment strength was 942 with 228 additional troops; total, 1,170.

Regiment lost during service 34 Enlisted men killed and mortally wounded and 4 Officers and 216 Enlisted men by disease.

Total 254, Additionally, 59 desertions and 8 unaccounted.