(3-Aminopropyl)triethoxysilane (APTES) is an aminosilane frequently used in the process of silanization, the functionalization of surfaces with alkoxysilane molecules.

[2] Thermoplastics are treated with oxygen plasma to functionalize surface molecules, and subsequently coated with an aqueous 1% by volume APTES solution.

PDMS is treated with oxygen plasma and placed in contact with the functionalized thermoplastic surface.

Octa(3-aminopropyl)silsesquioxane can be obtained in a one step hydrolytic condensation using APTES and hydrochloric or trifluoromethanesulfonic acid (CF3SO3H).

[3] APTES-functionalized surfaces have been shown to be nontoxic to embryonic rat cardiomyocytes in vitro.