50911949ENSG00000165629ENSMUSG00000025781P36542Q91VR2NM_001001973NM_005174NM_001320886NM_001112738NM_020615NM_001374641NP_001001973NP_001307815NP_005165NP_001106209NP_065640NP_001361570The human ATP5F1C gene encodes the gamma subunit of an enzyme called mitochondrial ATP synthase.

Mitochondrial ATP synthase catalyzes adenosine triphosphate (ATP) synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.

ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel.

The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3.

Alternatively spliced transcript variants encoding different isoforms have been identified.