He was named second-team Class 5A All-State after posting six interceptions, three fumble recoveries, three blocked kicks and allowing just one touchdown reception as a senior in 2001.

As a sophomore, Ross played at Fox Tech High School in San Antonio, Texas.

He played in thirteen games behind Nathan Vasher at left cornerback in 2003, coming up with 27 tackles (23 solos), a stop for a loss and two pass break-ups.

At the end of the season, he won the first of two Rose Bowl Championships As a junior, Ross earned All-Big 12 Conference honorable mention.

He earned All-American and All-Big 12 Conference first-team honors, in addition to being named the Thorpe Award winner (nation's top defensive back).

Ross was part of a Texas recruiting class which contained future NFL players Rodrique Wright, Justin Blalock, Brian Robison, Kasey Studdard, Lyle Sendlein, David Thomas, Selvin Young, and Vince Young.

[8] In his second NFL season in 2008, Ross recorded 52 tackles (4 for loss), 8 passes defended and 3 interceptions (58 return yards including a 50-yard TD).

[9] The Giants went 12–4 that year, good for the best record in the NFC, but fell to the rivaled Philadelphia Eagles in the divisional round of the 2008–09 NFL playoffs.

The Giants, despite being out of the playoff picture, ultimately placed Ross on the injured reserve list on December 31, 2009, just days before the final game of the season.

[12] The Jacksonville Jaguars signed cornerback Ross to a three-year, $15 million contract during the March free agency period in 2012.

[13] The transition to Jacksonville was difficult for Ross, who won two Super Bowls in New York, as the Jaguars finished 2–14, tied for the league's worst record.

Ross drew the ire of Jaguars fans by describing his time in Jacksonville as "a nice paid vacation to Florida".

[14] Ross was released after the start of free agency on March 8, 2013, by newly hired general manager Dave Caldwell.

[21] During his early days at Texas in 2003,[22] Ross began dating Longhorn track and field star, Sanya Richards-Ross, who is a 4-time Olympic Gold Medalist.