Abd al-Rahman al-Kayyali (Arabic: عبد الرحمن الكيالي; 1887 – 13 September 1969) was a physician from the city of Aleppo and member of the Syrian independence movement who served as the Minister of Justice and Education for two terms.

Born in Aleppo, al-Kayyali studied medicine at the Lebanese American University and graduated in 1914.

In the meantime, he served as the Minister of Justice and Education during the premiership of Jamil Mardam Bey, Saadallah al-Jabiri and Faris al-Khoury,[4] from 1936 to 1939 and from 1943 to 1945.

[2] As a representative of the Aleppan bourgeoisie and a nationalist activist, al-Kayyali built strong ties with leaders of Syria's first independence movement, including Ibrahim Hananu, leader of the so-called Hananu Revolt against French rule.

Kayyali can be considered one of the most prestigious citizens of Aleppo of his time and a Western educated proponent of anti-colonial nationalist ideology.