[1] The watershed of the creek has an area of 17.4 square miles (45 km2) and occupies portions of nine municipalities in northeastern Luzerne County.

The creek then continues south for more than a mile before turning southeast and eventually entering Frances Slocum Lake.

On the southeastern end of the lake, the creek turns east-northeast for more than a mile, entering a deep valley.

It then turns south-southeast for a few miles, entering West Wyoming flowing through a water gap.

It then turns southwest for more than a mile, entering Forty Fort and reaching its confluence with the Susquehanna River.

[1] Abrahams Creek joins the Susquehanna River 192.14 miles (309.22 km) upstream of its mouth.

[8] The peak annual discharge of Abrahams Creek at US Route 11 has a 10 percent chance of reaching 1,200 cubic feet per second (34 m3/s).

The peak annual discharge of Abrahams Creek at its mouth has a 10 percent chance of reaching 950 cubic feet per second (27 m3/s).

[9] The specific conductance of Abrahams Creek near Dallas ranged from 83 to 185 micro-siemens per centimeter at 25 °C (77 °F) in the early 1970s.

[4] In the early 1970s, the water temperature of the creek near Dallas in several measurements ranged from 8 to 22 °C (46 to 72 °F).

[1] The highest point in the watershed is on Bunker Hill, at slightly over 1,500 feet (460 m) above sea level.

In the early 20th century, part of the creek above The Hollow had grouted stone walls, which were completed in the 1930s.

[2] The creek's mouth is in the United States Geological Survey quadrangle of Pittston.

The Bunker Hill-Mount Lookout Ridge is too steep to be developed, but many other areas of the watershed could easily be urbanized.

[5] A total of 51 percent of the watershed of Abrahams Creek consists of forested land.

[4] Abrahams Creek is the main source of flooding in West Wyoming, Forty Fort, and Swoyersville.

The Slocum Dam, which is upstream of West Wyoming, also helps to reduce flooding on the creek.

The creek has been experienced extensive modifications, such as narrowing and riprap installation, in The Hollow to accommodate West Eighth Street.

Historically, wetlands formed the sources of many headwater streams in the area, but many have been drained or flooded by impoundments.

[5] Abrahams Creek is one of 19 streams in Luzerne County to be designated for stormwater management.

[15] Abrahams Creek was entered into the Geographic Names Information System on August 2, 1979.

[11] Extensive logging and intense agriculture were historically done in the watershed of Abrahams Creek.

A concrete slab bridge carrying State Route 1021/East Eighth Street was built in 1925.

A prestressed box beam bridge carrying State Route 1036/Carverton Road was constructed over the creek in 1976.

[17] The entire watershed of Abrahams Creek, including all of the streams and wetlands, has been significantly modified by both historical and modern land uses in the area.

The natural surface water hydrology of the watershed was substantially modified by projects of the United States Army Corps of Engineers and the Pennsylvania Department of Environmental Protection from the 1950s until the 1990s.

[19] Damaging flooding in 2006 caused the Abrahams Creek Watershed Assessment and Project Prioritization to be created.

[4] Nearly all of the watershed of Abrahams Creek is biologically degraded, with the only exceptions being several headwater streams.

[20] Wild trout naturally reproduce in a section of a tributary of the creek in West Wyoming.

[21] There is an herbaceous wetland along Abrahams Creek just upstream of where it enters Frances Slocum Lake.