Acanthoscurria theraphosoides is a species of spider from the family Theraphosidae (tarantulas), found in Peru, Bolivia, Brazil, and French Guiana.

[1] F. O. Pickard-Cambridge collected a mature female as his reference specimen (holotype) during his trip to the Lower Amazon, specifically in Pará state, Brazil.

[1][4] In the exotic pet hobby, there is another larger species often mistakenly traded under this name Acanthoscurria brocklehursti with alternating light and dark banding on the legs.

It is sometimes called the giant black and white tarantula because it can reach a leg span of 18–23 cm (7–9 in).

Scientifically, this is a thinner banded regional variant of Acanthoscurria geniculata, also from the Amazon basin.