[1] Museum building and the archaeological site are located in the north-eastern part of the city of Samarkand in the Central Asian country of Uzbekistan.

[3] The museum was conceived as the place that will share the story about the founding of the city of Samarkand, its subsequent history, as well as the settlement of Afrasiyab.

The museum features a variety of exhibits, including not only artifacts found during excavations in Afrasiyab and Samarkand but its wider region as well.

[2] One notable exhibit are the uniquely preserved Afrasiab murals of Samarkand palace belonging to the period of Ikhshid Dynasty from the 7th-8th centuries.

In December 2015, as a part of cultural cooperation between Uzbekistan and Azerbaijan, Azerbaijani pavilion was opened at the Afrasiab Museum.