The virus is widespread in captive populations of Pogona vitticeps, known commonly as the central bearded dragon, in the United States.

Agamid Adenovirus is becoming widespread in the United States, with several breeders admitting infection and shutting down their current projects.

A report from Louisiana State University [5] found that baby and juvenile Bearded Dragons have a high mortality rate associated with this virus.

Coinfections with other agents such as Isospora amphibolouri, a coccidia, and dependovirus, a genus of [5] Parvovirus may play roles in clinical presentation of disease.

Husbandry factors such as temperature range, diet, population density, and other stressors also are likely to play significant roles in clinical presentation.