Agbozume or Klikor-Agbozume is a town in Ketu Municipal District in the Volta Region of southeastern Ghana.

Agbozume is a settlement of the Somey people, whose subordinate position to the Anlo was confirmed in 1912 when Francis Crowther, Secretary for Native Affairs in the Gold Coast included Agbozume in the Anlo State under his friend Togbi Sri II.

Awanyedor and Akaga who were sons of Torgbui Wenya- the founder of Anlo State, left Anloga to found Keta as a fishing village.

Majority of the Keta people escaped across the lagoon to Klikor and Agbozume was built partly on land granted by Klikor and also on land seized from the Whlis (Ewe for weaver birds), the original inhabitants who were defeated in war.

In December 2013, 600 residents from Agbozume took part in a protest against the Kesington Salt Factory, who they claimed had endangered their livelihoods by creating a crater to remove sand to build a road.