Agios Polykarpos (Greek: Άγιος Πολύκαρπος) is a seaside settlement in Nafpaktia, Aetolia-Acarnania, Greece, located 6 km west of Antirrio and 15 km southwest of Nafpaktos.

[2][3] According to the 2021 census, it had 26 inhabitants.

[1] The settlement is named after the church of Saint Polycarpus.

In 1981, Agios Polykarpos became a settlement of the community of Makyneia.

In 1989, Agios Polykarpos became part of the municipality of Antirrio, which is a municipal unit of the municipality of Nafpaktia since 2011.