It planned to begin operations in October 2009 using a Boeing 737-400 aircraft with daily services to New York City and Miami.

On 15 December 2008, the US Department of Transportation issued an FAA license which granted Air Dominicana the right to operate flights to the United States.

The airline was expected to begin its operations in May 2008 with a Boeing 737-300, but the launch date was postponed several times until 16 October 2009.

Originally, Dominicana Air was also owned by Futura International Airways until the airline failed to re-finance itself, therefore ceasing operations on 8 September 2008.

Air Dominicana planned to launch services with flights to Miami and New York City from Santo Domingo.