Hafsatu Ajoke Muhammed (born 23 May 1941) is a Nigerian conservationist and the fourth First Lady of Nigeria.

She is the widow of General Murtala Muhammed who was Nigerian Head of State from 29 July 1975 to 13 February 1976.

[2] Ajoke married Murtala Muhammed in 1963.

[3] She trained as a dental therapist but developed an interest in plants.

[4][6] She has 5 living children and launched the Murtala Muhammed Foundation in memory of her husband alongside his family.