Safinatu Buhari (née Yusuf) (11 December 1952 – 14 January 2006) was a Nigerian teacher and First Lady of Nigeria from 1983 to 1985.

[1] She was of the Fulani tribe of Northern Nigeria and hailed from Mani Local Government in Katsina State.

When Muhammadu Buhari's government was overthrown by Ibrahim Babangida, she relocated to Kaduna with her children.

Following the military coup that removed Muhammadu Buhari as president on August 27,1985, when he was released from prison, he divorced Safinatu shortly after; the reason for Buhari's divorce from his first wife has remained unknown.

[6][8] She was largely unknown by Nigerians as she did not have her own office or personal staff in Dodan Barracks.