Alfred Louis Nesser (June 6, 1893 – March 11, 1967) was a professional American football guard and end.

He won NFL Championship titles with the Akron Pros in 1920 and the New York Giants in 1927.

During his career, Nesser played against Charlie Copley, Fritz Pollard and Jim Thorpe.

Although he didn't play college football, prior to the formation of the NFL, Nesser played in the "Ohio League" for the Columbus Panhandles and the Canton Professionals (later renamed the Canton Bulldogs).

This biographical article relating to an American football offensive lineman born in the 1890s is a stub.