The southern terminus of the route is at an intersection with SR 18 approximately 3 miles (4.8 km) northwest of Fayette.

The highway reaches its northern terminus approximately 2 miles (3.2 km) south of Guin at an intersection with SR 118.

SR 107 is aligned on a two-lane road as it travels through Fayette and Marion counties.

The route serves to connect the towns at its southern and northern termini and does not pass through any incorporated cities or towns.

[2] SR 142 west (11th Avenue W)