It heads northeast through forested areas, on two-lane undivided 11th Avenue.

The highway enters the city limits of Guin at a crossing over Wickett Creek.

The route turns more to the east as it begins to pass homes and businesses.

It intersects the eastern terminus of Marion County Route 16 (CR 16).

SR 142 continues east into the commercial downtown of Guin, ending at an intersection with US 43/US 278/SR 118/SR 171.