State Route 95 (SR 95) is a 41.700-mile-long (67.110 km) state highway that extends from SR 52 near Columbia in Houston County to U.S. Route 431 (US 431) in southern Eufaula in Barbour County.

South of Columbia, the route is designated as County Road 95 that goes south through Gordon and then reaching the Florida state line and continuing as County Road 164, which leads to County Road 271 and Sneads.

It intersects SR 134's eastern terminus as it exits town.

It runs parallel with the Chattahoochee River (Alabama-Georgia State Line) as it proceeds north.

Then, the route passes through White Oak and crosses over the White Oak Creek before reaching its northern terminus at US 431/SR 1 south of Eufaula.