[1] Zaccone began competing as a child; in 2008, he was regional mini-bike champion and fourth at the national level.

[2] He made his international debut in 2013 by participating, with the Honda Italia team, in the Imola Grand Prix of the European Junior Cup.

In 2016, Zaccone, together with Axel Bassani, rode for the San Carlo Team Italia with which he took part in the races in the European section of the Supersport World Championship.

In 2017, he moved to the MV Agusta Reparto Corse team with which he competed again for the European Cup of the Supersport World Championship.

[6] In 2020, Zaccone made his debut in the world championship, racing in the MotoE class with the Trentino Gresini team with Matteo Ferrari as his teammate.