The 2021 Spanish motorcycle Grand Prix (officially known as the Gran Premio Red Bull de España) was the fourth round of the 2021 Grand Prix motorcycle racing season and the first round of the 2021 MotoE World Cup.

After winning the Portuguese motorcycle Grand Prix, Fabio Quartararo leads the rider standings with 61 points, 15 more than Francesco Bagnaia.

Aprilia, KTM and Honda are enclosed in 5 points (25, 22 and 20).

Aprilia Racing Team Gresini is fifth with 27 points.

Below are the standings for the top five riders, constructors, and teams after the round.