In June 1995, Lowe helped the National Park Service rescue several Spanish climbers on 20,320-foot (6,190 m) Denali in Alaska.

Before a rescue team could assemble, one of the climbers fell 4,200 feet (1,300 m) to his death from the mountain's Upper West Rib.

Lowe, Mark Twight and Scott Backes were lifted by military helicopter to a plateau above the Spaniards, scaled down a 400-vertical foot, 50-degree slope of ice and rock, to reach them and determined that one needed immediate evacuation.

Amid snowy conditions, he at first dragged, then carried him on his back up the steep slope at high altitude.

[4] Plans called for Lowe and Anker to be part of the team that would ski down, to become the first Americans to ski down from the summit of an 8,000-meter peak; while Bridges was part of a three-man film team that was to shoot an NBC documentary of the expedition for The North Face.

The Alex Lowe Charitable Foundation was established in his honor to provide direction and financial support to humanitarian programs in mountain regions around the world.