Alfred Singer (born December 10, 1946) is an American immunologist who works at the National Institutes of Health (NIH), where he is the Chief of the Experimental Immunology Branch of the National Cancer Institute (NCI) Center for Cancer Research.
[1] He is best known for his work regarding lymphocyte development, particularly the differentiation of immature CD4+8+ (double positive) thymocytes into mature T cells.
Singer's work is foundational in the understanding of T cells and MHC-restricted antigen recognition.
[4] Singer was raised in Port Jervis, New York, the eldest son of a baker.
He studied philosophy at the Massachusetts Institute of Technology, where he received his BS in 1968 and met his wife, Dinah Singer.