[2] She is able to create incredibly lifelike representations of real people by touch and memory alone; her sculptures of the Fantastic Four and other superheroes are frequently depicted.

[3] A caring, sensitive character,[4] she has been a romantic interest, confidante, and eventual wife of The Thing, a member of the Fantastic Four who is frequently ashamed of his monstrous appearance.

[10] Alicia initially aids the Puppet Master out of obedience in his first scheme against the Fantastic Four, though she immediately senses the "gentle" and "sensitive" spirit of the Thing when she first feels his palpably monstrous face.

A subsequently published story explains that the Puppet Master had been responsible for her permanent blindness, which was caused by an explosion of radioactive clay during his fight with a rival.

The character plays an integral role in one of the most acclaimed comic book stories of the Silver Age, "The Coming of Galactus", in Fantastic Four #48–50 (March–May 1966).

In that story arc, the Silver Surfer first comes to Earth as a herald to the powerful, world-destroying being Galactus, and crashes into Alicia's apartment after fighting the Fantastic Four.

These three villains planned to attack the wedding, but at the last moment Puppet Master stopped them, with the (unwilling) help of Dragon Man.

[23] After the Fantastic Four have disbanded following the collapse of the multiverse, Peter Parker purchases the Baxter Building to keep it safe until the team are ready to come back together, including a statue of the FF in the entrance hall that was made by Alicia.

[27] In the aftermath of the 2020 crossover “Empyre”, Ben and Alicia adopted two orphans, the Kree boy Jo-Venn and the Skrull girl N’Kala.

Kai Young of Screen Rant stated the empathy Alicia Masters demonstrates makes the character a "gentle presence" among the Fantastic Four and complimented her relationship with Ben Grimm.

[29] David Harth of Comic Book Resources praised how Alicia Masters overlooks Ben Grimm's appearance and values his true nature, calling their relationship a "huge moment for every fan".

She finds a depressed Ben in the park; her simple gesture of friendship instantly places her in mortal danger from Doctor Doom.