[5][6][7] It is one of the six AIIMS healthcare established in 2012, and it operates autonomously under the Ministry of Health and family welfare (India), Government of India under the Pradhan Mantri Swasthya Suraksha Yojna (PMSSY).

The All-India Institute of Medical Sciences (Amendment) Bill, 2012, was introduced in the Lok Sabha on 27 August 2012.

[12][13] Bill got its assent from the President of India, Pranab Mukherjee on 12 September 2012 and the Act came into force.

[14] The proposed measure will help the Centre change the status of the six new AIIMS registered under the Indian Societies Registration Act to be autonomous body corporate on the lines of the existing AIIMS in Delhi.

[4] Being located in an easily accessible location in the major city of Raipur, the institute answers to the medical needs of a majority of the population of Central India including Chhattisgarh, parts of eastern Maharashtra (Vidarbha Region), Madhya Pradesh and Odisha.