Allylamine

All three allylamines, mono-, di-, and triallylamine, are produced by the treating allyl chloride with ammonia followed by distillation.

[4] Pure samples can be prepared by hydrolysis of allyl isothiocyanate.

Pharmaceutically important allylamines include flunarizine and naftifine; the latter spurred the development of Petasis' borono-Mannich reaction.

Flunarizine aids in the relief of migraines while naftifine acts to fight common fungus causing infections such as athlete's foot, jock itch, and ringworm.

[7] Allylamine, like other allyl derivatives is a lachrymator and skin irritant.

NFPA 704 four-colored diamond Health 4: Very short exposure could cause death or major residual injury. E.g. VX gas Flammability 3: Liquids and solids that can be ignited under almost all ambient temperature conditions. Flash point between 23 and 38 °C (73 and 100 °F). E.g. gasoline Instability (yellow): no hazard code Special hazards (white): no code
Flunarizine and naftifine are pharmacologically active allylamines.