All three allylamines, mono-, di-, and triallylamine, are produced by the treating allyl chloride with ammonia followed by distillation.
[4] Pure samples can be prepared by hydrolysis of allyl isothiocyanate.
Pharmaceutically important allylamines include flunarizine and naftifine; the latter spurred the development of Petasis' borono-Mannich reaction.
Flunarizine aids in the relief of migraines while naftifine acts to fight common fungus causing infections such as athlete's foot, jock itch, and ringworm.
[7] Allylamine, like other allyl derivatives is a lachrymator and skin irritant.