α-Cyclodextrin (alpha-cyclodextrin), sometimes abbreviated as α-CD, is a hexasaccharide derived from glucose.

It is related to the β- (beta) and γ- (gamma) cyclodextrins, which contain seven and eight glucose units, respectively.

Cyclodextrins tend to bind other molecules in their quasi-cylindrical, lipophilic interiors.

α-Cyclodextrin is marketed for a range of medical, healthcare, and food and beverage applications.

For industrial use, they are manufactured by enzymatic degradation from vegetable raw materials, such as corn or potatoes.