In ancient Egyptian religion, Ammit played an important role during the funerary ritual, the Judgment of the Dead.

[6] The combination of three deadly animals of the Nile: crocodile, lion, and hippopotamus, suggests that no one can escape annihilation, even in the afterlife.

In the Papyrus of Ani, Ammit is adorned with a tri-colored nemes,[14][15] which were worn by pharaohs as a symbol of kingship.

In this scene, Ammit is shown with other Egyptian gods in Duat, waiting to learn if she can consume the heart of the deceased.

Around the twenty-first dynasty, the Judgment of the Dead scene was painted on the interior and exterior of coffins.

The coffin lid of Ankh-hor, a chief from the twenty-second dynasty featured Ammit bearing the head of a hippopotamus, and the body of a dog with rows of paps.

Demons in ancient Egyptian religion had supernatural powers and roles, but were ranked below the gods and did not have a place of worship.

Guardian demons that appeared as a hybrid of animals were an amalgamation of traits meant to be feared and to differentiate them from deities associated with humanity.

[22] Prior to the New Kingdom and the creation of Chapter 125 in the Book of the Dead, Ammit did not have a large presence in ancient Egyptian religion.

[23] Throughout the First Intermediate Period and the Middle Kingdom, a collection of spells was created to form the Coffin Texts.

In Spell 310, Khonsu burned hearts heavier than the feather of ma'at during the Judgment of the Dead.

[3][32] Saba Mubarak portrays Ammit in the Marvel Cinematic Universe (MCU) television series Moon Knight (2022).

In Primeval, Ammit was a Pristichampsus that came through an Anomaly (a gateway in time) to ancient Egypt, where people believed it to be a god.