[citation needed] The following week, Pavlyuchenkova made her Fed Cup debut, where Russia faced Italy in the semifinals, dropping her sole match to Francesca Schiavone.

En route to the final, she moved past the likes of Anna Tatishvili, Polona Hercog and Klára Zakopalová to reach the semifinals where she beat Anastasija Sevastova.

[17] Pavlyuchenkova continued her good form in Cincinnati, beating Hantuchová and defending champion Elena Dementieva to advance to the third round where she moved past 13th seed Shahar Pe'er.

[26][27] Pavlyuchenkova had a dismal grass-court campaign, dropping her opening match in Eastbourne to Bojana Jovanovski and falling in the second round of the Wimbledon Championships to Nadia Petrova in straight sets.

[citation needed] Pavlyuchenkova's form improved after Wimbledon when she made the quarterfinals in Båstad and then went on to reach her first final of the year at the Washington Open where she was beaten by Magdaléna Rybáriková.

In the Fed Cup semifinals against Slovakia, she lost her singles match to Dominika Cibulková but Russia nevertheless advanced to the final by winning the decisive doubles rubber.

The pair also won the Premier Mandatory-level Madrid Open by defeating Cara Black and Marina Erakovic in the final, it is Pavlyuchenkova's biggest career doubles title to date.

[55] Pavlyuchenkova was the 29th seed at the Australian Open and defeated Teliana Pereira and Mandy Minella to reach the third round where she lost to eventual semifinalist Agnieszka Radwańska in three sets.

[62] After an early loss to Garbiñe Muguruza in Tokyo, Pavlyuchenkova scored her first win over Ivanovic, via retirement from the Serb, en route the second round in Wuhan where she lost to Casey Dellacqua.

At the Monterrey Open, Pavlyuchenkova recorded her first victories of the year by defeating Anna Karolína Schmiedlová and Johanna Larsson to reach the quarterfinals where she lost to second seed Sara Errani.

As the defending champion in Moscow, she carried on her good form by advancing to her third final of the year but saw her title defence come to an end in the hands of compatriot Svetlana Kuznetsova.

At the Wimbledon Championships, Pavlyuchenkova was the 21st seed and she moved past Hsieh Su-wei and Yulia Putintseva to reach the third round where she upset Timea Bacsinszky to advance to the second week of a Grand Slam tournament for the first time since the 2011 US Open.

[90] She then made the quarterfinals in Sydney by claiming excellent victories over Samantha Stosur and defending champion Svetlana Kuznetsova before falling to Eugenie Bouchard in straight sets.

The following month, in Monterrey, Pavlyuchenkova reached the quarterfinals after defeating Tatjana Maria and qualifier Kristie Ahn before surviving fifth seed Tímea Babos to cruise into her first semifinal in eleven tries, her first since the Kremlin Cup in 2015.

[95] After an unsuccessful Fed Cup campaign against Belgium for a place in the World Group, dropping her singles match to Elise Mertens, with the Russian team ultimately losing the tie 2–3, Pavlyuchenkova reached her second final of the year in Rabat.

Kicking off her clay-court season in Stuttgart, Pavlyuchenkova finally gained some momentum by making her first ever quarterfinal at the tournament, beating Madison Keys and second seed Garbiñe Muguruza, the latter by via retirement.

There, she came from a set and a break down to upset fifth seed Sloane Stephens and thus, earned herself a berth in her fifth Grand Slam quarterfinal, where she faced first-time major quarterfinalist Danielle Collins.

Seeded third in Monterrey, Pavlyuchenkova sauntered into the last eight with wins over Anna Blinkova and Ivana Jorović with a combined loss of just three games but there, she was eliminated by eventual runner-up Victoria Azarenka in straight sets.

[113] On Fed Cup duty against Italy for a place in World Group II, Pavlyuchenkova won her singles matches over Jasmine Paolini and Martina Trevisan with the Russian team eventually winning the tie 4–0.

Pavlyuchenkova's form mid-season did not improve as she suffered a five-match losing streak after Stuttgart, which includes losses at the French Open and Wimbledon,[115][116] resulting in her ranking falling out of the top 40 to as low as No.

[117] Pavlyuchenkova started off the Asian swing by recording by her best result of the year by making the final of the Pan Pacific Open, her second at the tournament, defeating the likes of Dayana Yastremska, Bertens, Misaki Doi and Angelique Kerber en route, where she finished runner-up to Naomi Osaka.

[119] She then bounced back by reaching her second final of the season at the Kremlin Cup, also her third at the tournament, by seeing off seventh seed Maria Sakkari, qualifier Varvara Gracheva, Kudermetova and Karolína Muchová en route.

[125] Pavlyuchenkova played one more tournament before the tour was suspended in March due to the COVID-19 pandemic, making the second round at the Dubai Championships after upsetting fourth seed and defending champion Belinda Bencic but there, she lost to Kontaveit.

[132] She then scored straight-set wins over Misaki Doi and Anastasija Sevastova to reach the third round at the Yarra Valley Classic, losing to eventual finalist Garbiñe Muguruza.

[133] After that, Pavlyuchenkova competed at the Phillip Island Trophy and defeated Ajla Tomljanović in her opening match but then lost to eventual champion Daria Kasatkina in three sets.

Partnering Andrey Rublev, the first-time pairing sailed to the final, and took home the gold medal over compatriots Aslan Karatsev and Elena Vesnina, after saving a match point.

[157] The subsequent four tournament appearances of Pavlyuchenkova saw her net just one quarterfinal result, with a run to the last eight on home soil, in Moscow, where she lost to Markéta Vondroušová,[158] besides taking a loss in the hands of youngster Leylah Fernandez in the third round of Indian Wells, despite having led by a set and a break in the latter.

In doubles, she partnered Wimbledon champion Elena Rybakina and reached the third round, defeating fifth seeded pair of Ukrainian Lyudmyla Kichenok and Latvian Jeļena Ostapenko en route.

[citation needed] The following year, at the Miami Open, she recorded her 500th career win over Shelby Rogers, making her the sixth Russian woman to achieve the milestone after Kuznetsova, Sharapova, Dementieva, Petrova and Zvonareva.

[185] They competed as neutrals, without any national flag or symbol, but the Czech government passed a resolution banning all Russian and Belarusian athletes from entering the country due to the war in Ukraine.