[citation needed] Potapova's other junior highlights include semifinal appearances at the Trofeo Bonfiglio and the Orange Bowl championships, both Grade-A events.

[citation needed] She then made her WTA Tour debut, after having received a wildcard to compete in the qualifying rounds of the Premier Mandatory event in Miami, defeating Maria Sakkari for her first top-100 win, before falling to Jana Čepelová in straight sets.

She pounced on her chances, steering through all her matches in straight sets to make her Grand Slam main-draw debut defeating Elizaveta Kulichkova in the last round.

[citation needed] Potapova started 2018 with a final appearance at the Sharm El Sheikh $15k event, but was upset by world No.

[6] Potapova made her Fed Cup debut for Russia, but lost to the higher-ranked Viktória Kužmová and was unable to lead her country to the victory on that weekend.

She defeated two top-100 players and came out of nowhere to make her maiden WTA final,[8] but faltered at the last hurdle as she fell to fellow 17-year-old Olga Danilović in a historic clash between the new generation.

[9] She led by a break in the deciding set, but failed to close out the win but still managed to make her top-150 debut with this amazing run.

[12] Her season ended with a tough, but encouraging loss to eventual semifinalist and eighth seed Anett Kontaveit in the opening round of the Kremlin Cup despite leading by a break in the final set.

[14] Potapova received entry to the main draw of the Australian Open and played her first match against Pauline Parmentier, defeating her in straight sets.

[17] At the same tournament, she also reached the doubles semifinal alongside Anna Blinkova, but lost to compatriots Ekaterina Alexandrova/Vera Zvonareva in three sets.

[citation needed] Beginning her 2021 season at the first edition of the Abu Dhabi Open, Potapova lost in the first round to ninth seed Maria Sakkari.

[44] The Russian saved match points against Nina Stojanović in the first round of the Birmingham Classic[45] and reached her second WTA quarterfinal of the year with a comfortable win over Mladenovic.

[56] However, she made her first major quarterfinal in doubles, alongside Rebecca Peterson, although they lost to eventual finalists Beatriz Haddad Maia and Anna Danilina, after leading by a set and a break.

[63] At the same tournament, she won her third doubles title with Yana Sizikova defeating compatriots Angelina Gabueva and Anastasia Zakharova.

[citation needed] Potapova won her second WTA title at the Linz Open in February, defeating sixth seed Petra Martić in the final,[64] having got past Lucia Bronzetti,[65] Jule Niemeier,[66] Anna-Lena Friedsam[67] and Markéta Vondroušová[68] on her way to the championship match.

In March, the WTA issued a formal warning to Potapova for wearing a T-shirt of Russian soccer team Spartak Moscow before a match in Indian Wells.

[78] Moving onto the grass-court season, she reached the semifinals at the Birmingham Classic, overcoming Marta Kostyuk,[79] Caty McNally[80] and Harriet Dart[81] en route to a last four match-up with second seed and eventual champion Jelena Ostapenko which she lost in three sets.

[82] At Wimbledon, where she was seeded 22nd, Potapova defeated qualifiers Celine Naef[83] and Kaja Juvan to reach the third round at this major for the first time.

[85] In September at the San Diego Open, Potapova recorded wins over Alycia Parks[86] and top seed Ons Jabeur to make it into the quarterfinals,[87] where she lost to wildcard entrant Sofia Kenin.

[91] Seeking to defend her title at the Linz Open, she defeated Italians Sara Errani[92] and Elisabetta Cocciaretto,[93] before losing in the quarterfinals to second seed Ekaterina Alexandrova.

[94] At the Dubai Tennis Championships, Potapova overcame Zhu Lin[95] and Lucia Bronzetti[96] to reach the third round, where she lost to sixth seed Zheng Qinwen.

[101] At the French Open, Potapova recorded wins over Kamilla Rakhimova,[102] Viktorija Golubic[103] and Wang Xinyu,[104] but was then double bagled by top seed Iga Świątek in a fourth round match which lasted a mere 40 minutes.

[105] On the grass-courts of Birmingham in June, she defeated Elina Avanesyan,[106] Lucia Bronzetti[107] and second seed Barbora Krejčíková[108] to reach the semifinals, where her run was ended by Ajla Tomljanović.

[109] Potapova made her second semifinal of the year at the Cleveland Open, overcoming Diane Parry,[110] Clara Tauson[111] and Ana Bogdan,[112] before losing to wildcard entry and eventual champion McCartney Kessler.

[113] She defeated 23rd seed Leylah Fernandez[114] and qualifier Varvara Lepchenko[115] to reach the third round at the US Open, where she lost to Karolína Muchová.

[116] Potapova began her 2025 season at the Brisbane International, making it through the first round when her opponent Ana Bogdan retired due to heat-related illness[117] and then defeating 16th seed Dayana Yastremska.

[119] At the Australian Open, Potapova overcame qualifier Tamara Zidanšek,[120] before losing in three sets to 27th seed Anastasia Pavlyuchenkova in the second round.

[124] The following week, as top seed at the Transylvania Open in Cluj-Napoca, she won her third WTA Tour singles title overcoming Julia Grabher,[125] Viktorija Golubic,[126] Ella Seidel[127] Aliaksandra Sasnovich.