Anastasia the Roman (died c. 250) was 3rd-century Christian saint and nun who was martyred during the reign of Roman emperor Decius.

Anastasia was orphaned at the age of three and was raised in a convent, where she became renowned for her asceticism.

During the persecutions under the Emperor Decius, she was apprehended, tortured, and beheaded by a city administrator named Probus.

Her feast day is celebrated on 29 October.

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