[1][2][3] André began his stand-up comedy career in 2015, performing at local clubs and bars in Lisbon.

[9][10] The show was noted for its humorous exploration of life's uncertainties and received a series of 4[11][12] and 5-star[13][14] reviews from a series of publications including The Sunday Express and The Telegraph,[15] where he made their list of "Funniest Jokes of the 2023 Fringe".

[16][17] André De Freitas has done tour support for comedians Jim Jefferies, Russell Peters, Iliza Schlesinger, TJ Miller, Alan Carr and Sam Jay.

André co-wrote and participated in 4-part tutorial series with Oracle Red Bull Racing driver Sergio "Checo" Pérez and Formula 1 World Champion Max Verstappen for crypto marketplace Bybit.

[18] André de Freitas was part of the BBC World Service Arts Hour Comedy Special of 2024.