Early theater roles include Moritz Stiefel in Frank Wedekind's Spring Awakening[1] and Eugene Morris Jerome in Neil Simon's Brighton Beach Memoirs.

Film roles include Simon in South of Wawa, written by bestselling Canadian novelist and screenwriter Lori Lansens;[2] Kazan, the autistic man, in Vincenzo Natali's Cube; and Donald in Oh, What a Night, for which he was nominated for a 1992 Genie Award for Best Supporting Actor.

[6] Besides his work in Hollywood, Andrew Miller also has a career as a teacher at a school for children with autism and other conditions.

Miller attended McGill University in Montreal, Quebec, Canada, where he studied Political Science and Economics.

[1] In March 2007, Miller became engaged to Eden Riegel who had been friends with Cameron Mathison (Ryan Lavery on All My Children).